A Facile Route to Polysubstituted N-Benzyl Pyroglutamates
Author:
Affiliation:
1. Department of Chemistry, National Sun Yat-Sen University, Kaohsiung 804, Taiwan
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol0344164
Reference34 articles.
1. Pyroglutamic acid: a versatile building block in asymmetric synthesis
2. A short, efficient chiral synthesis of a novel cholinergic channel activator, ABT-418 [(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole], from (S)-pyroglutamic acid
3. Synthesis of a potent (±)-4-(2-hydroxyphenyl) analogue of the acromelic acids by dearomatising cyclisation of a lithiated N-p-methoxybenzyl-4-methoxy-1-naphthamide
4. Asymmetric deprotonation and dearomatising cyclisation of N-benzyl benzamides using chiral lithium amides: formal synthesis of (–)-kainic acid
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