Enhanced Heterologous Spinosad Production from a 79-kb Synthetic Multioperon Assembly-Reference-Cited by-同舟云学术

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Enhanced Heterologous Spinosad Production from a 79-kb Synthetic Multioperon Assembly

Published:2018-12-28 Issue:1 Volume:8 Page:137-147
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Song Chaoyi¹,Luan Ji¹,Cui Qingwen¹,Duan Qiuyue¹,Li Zhen¹,Gao Yunsheng¹,Li Ruijuan¹,Li Aiying¹,Shen Yuemao¹^ORCID,Li Yuezhong¹^ORCID,Stewart A. Francis²³,Zhang Youming¹,Fu Jun¹,Wang Hailong¹^ORCID

Affiliation:

1. Shandong University−Helmholtz Institute of Biotechnology, State Key Laboratory of Microbial Technology, School of Life Science, Shandong University, Binhai Road 72, 266237 Qingdao, People’s Republic of China

2. Genomics, Biotechnology Center, Technische Universität Dresden, Tatzberg 47-51, Dresden 01307, Germany

3. GenArc GmbH, BioInnovationsZentrum, Tatzberg 47, Dresden 01307, Germany

Funder

State Administration of Foreign Experts Affairs

Shandong Province

Ministry of Science and Technology of the People's Republic of China

Ministry of Education of the People's Republic of China

Shandong University

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Biochemistry, Genetics and Molecular Biology (miscellaneous),Biomedical Engineering,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.8b00402

Reference47 articles.

1. Computational identification and analysis of orphan assembly-line polyketide synthases

2. A New Golden Age of Natural Products Drug Discovery

3. Full-length RecE enhances linear-linear homologous recombination and facilitates direct cloning for bioprospecting

4. Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A

5. Yeast homologous recombination-based promoter engineering for the activation of silent natural product biosynthetic gene clusters

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