Hybrid Cas12a Variants with Relaxed PAM Requirements Expand Genome Editing Compatibility-Reference-Cited by-同舟云学术

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Hybrid Cas12a Variants with Relaxed PAM Requirements Expand Genome Editing Compatibility

Published:2024-05-31 Issue:6 Volume:13 Page:1809-1819
ISSN:2161-5063
Container-title:ACS Synthetic Biology
language:en
Short-container-title:ACS Synth. Biol.

Author:

Liu Zhenyu¹,Liu Huayi¹^ORCID,Huang Chaoqun¹,Zhou Qun¹,Luo Yunzi¹²³^ORCID

Affiliation:

1. Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China

2. Georgia Tech Shenzhen Institute, Tianjin University, Tangxing Road 133, Nanshan District, Shenzhen 518071, China

3. Haihe Laboratory of Sustainable Chemical Transformations, Tianjin 300192, China

Funder

National Key Research and Development Program of China

Special Project for Research and Development in Key areas of Guangdong Province

National Natural Science Foundation of China

Haihe Laboratory of Sustainable Chemical Transformations

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acssynbio.4c00103

Reference62 articles.

1. SnapShot: Class 2 CRISPR-Cas Systems

2. SnapShot: Class 1 CRISPR-Cas Systems

3. CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine

4. Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

5. Base editing: precision chemistry on the genome and transcriptome of living cells

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