Response Surface Methodology As a New Approach for Finding Optimal MALDI Matrix Spraying Parameters for Mass Spectrometry Imaging

Author:

Veličković Dušan1,Zhang Guanshi2,Bezbradica Dejan3,Bhattacharjee Arunima1,Paša-Tolić Ljiljana1,Sharma Kumar2,Alexandrov Theodore45,Anderton Christopher R.12ORCID,

Affiliation:

1. Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99352, United States

2. Center for Renal Precision Medicine, University of Texas Health-San Antonio, San Antonio, Texas 78284, United States

3. Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy, University of Belgrade, Belgrade 11000, Serbia

4. Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg 69117, Germany

5. Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California 92093, United States

Funder

National Institute of Diabetes and Digestive and Kidney Diseases

H2020 Research Infrastructures

H2020 Health

H2020 European Research Council

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

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