Design and Synthesis of a Focused Library of Diamino Triazines as Potential Mycobacterium tuberculosis DHFR Inhibitors-Reference-Cited by-同舟云学术

Design and Synthesis of a Focused Library of Diamino Triazines as Potential Mycobacterium tuberculosis DHFR Inhibitors

Published:2015-10-20 Issue:11 Volume:6 Page:1140-1144
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Lele Arundhati C.¹,Raju Archana¹,Khambete Mihir P.¹,Ray M. K.²,Rajan M. G. R.²,Arkile Manisha A.³,Jadhav Nandadeep J.³,Sarkar Dhiman³,Degani Mariam S.¹

Affiliation:

1. Department of Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Matunga (E), Mumbai 400019, India

2. Radiation Medicine Center, Bhabha Atomic Research Centre, Tata Memorial Hospital Annex, Parel, Mumbai 400012, India

3. Combichem-Bioresource Center, Organic Chemistry Division, CSIR-National Chemical Laboratory, Pune 411008, India

Funder

Indian Council of Medical Research

Council of Scientific and Industrial Research

Department of Science and Technology, Ministry of Science and Technology

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.5b00367

Reference28 articles.

1. Antifolates - Past, Present and Future

2. Update on Antifolate Drugs Targets

3. Dihydrofolate reductase inhibitors as antibacterial agents

4. WHO. GlobalTuberculosis Report 2014 (WHO/HTM/TB/2014.08), (2014.

5. Novel Saccharomyces cerevisiae Screen Identifies WR99210 Analogues That Inhibit Mycobacterium tuberculosis Dihydrofolate Reductase

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