Discovery of Novel Nonpeptidic Proteasome Inhibitors Using Covalent Virtual Screening and Biological Evaluation-Reference-Cited by-同舟云学术

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Discovery of Novel Nonpeptidic Proteasome Inhibitors Using Covalent Virtual Screening and Biological Evaluation

Published:2024-09-09 Issue: Volume: Page:
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Zhou Jiao¹^ORCID,Sang Xiaohong¹^ORCID,Wu Meixian²,Qian Tingli¹,Ciechanover Aaron¹³,An Jing²,Xu Yan²,Huang Ziwei¹²

Affiliation:

1. Ciechanover Institute of Precision and Regenerative Medicine, School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China

2. Department of Medicine, Division of Infectious Diseases and Global Public Health, School of Medicine, University of California at San Diego, La Jolla, California 92037, United States

3. Technion Rappaport Integrated Cancer Center, The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, Haifa 3109601, Israel

Funder

Ganghong Young Scholar Development Fund

Shenzhen-Hong Kong Cooperation Zone for Technology and Innovation

Shenzhen Science and Technology Program

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.4c00321

Reference44 articles.

1. THE UBIQUITIN SYSTEM

2. Drug discovery in the ubiquitin–proteasome system

3. The unravelling of the ubiquitin system

4. Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

5. The ubiquitin proteasome system — Implications for cell cycle control and the targeted treatment of cancer

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