Discovery of Investigational Drug CT1812, an Antagonist of the Sigma-2 Receptor Complex for Alzheimer’s Disease
Author:
Affiliation:
1. Cognition Therapeutics, 2403 Sidney Street, Suite 261, Pittsburgh, Pennsylvania 15203, United States
2. Acme Bioscience, Inc., 3941 East Bayshore Road, Palo Alto, California 94303, United States
Funder
National Institute of Neurological Disorders and Stroke
National Institute on Aging
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00048
Reference52 articles.
1. The amyloid hypothesis of Alzheimer's disease at 25 years
2. Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis
3. The case for soluble Aβ oligomers as a drug target in Alzheimer's disease
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5. The Amyloid-β Oligomer Hypothesis: Beginning of the Third Decade
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