Indole-Containing Pyrazino[2,1-<i>b</i>]quinazoline-3,6-diones Active against <i>Plasmodium</i> and Trypanosomatids-Reference-Cited by-同舟云学术

Indole-Containing Pyrazino[2,1-b]quinazoline-3,6-diones Active against Plasmodium and Trypanosomatids

Published:2022-01-11 Issue:2 Volume:13 Page:225-235
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Long Solida¹²,Duarte Denise³,Carvalho Carla⁴,Oliveira Rafael³,Santarém Nuno⁴,Palmeira Andreia¹⁵,Resende Diana I. S. P.¹⁵,Silva Artur M. S.⁶^ORCID,Moreira Rui⁷^ORCID,Kijjoa Anake⁵⁸,Cordeiro da Silva Anabela⁴⁹,Nogueira Fátima³^ORCID,Sousa Emília¹⁵^ORCID,Pinto Madalena M. M.¹⁵

Affiliation:

1. Laboratório de Química Orgânica e Farmacêutica, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal

2. Department of Bioengineering, Royal University of Phnom Penh, Russian Confederation Blvd, 12156 Phnom Penh, Cambodia

3. Global Health and Tropical Medicine (GHTM), Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, 1349-008 Lisboa, Portugal

4. Parasite Disease Group, IBMC-Instituto de Biologia Molecular e Celular, Rua Alfredo Allen, 4200-135 Porto, Portugal

5. CIIMAR - Centro Interdisciplinar de Investigação Marinha e Ambiental, Terminal de Cruzeiros do Porto de Leixões, 4450-208 Matosinhos, Portugal

6. QOPNA - Química Orgânica, Produtos Naturais e Agroalimentares, Departamento de Química, Universidade de Aveiro, Campus Universitário de Santiago, 3810-193 Aveiro, Portugal

7. Research Institute for Medicines and Pharmaceutical Sciences (iMed.UL), Faculdade de Farmácia, Universidade de Lisboa, 1649-019 Lisboa, Portugal

8. ICBAS-Instituto de Ciências Biomédicas Abel Salazar, Universidade do Porto, 4050-313 Porto, Portugal

9. Departamento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, 4050-313 Porto, Portugal

Funder

European Regional Development Fund

Funda??o para a Ci?ncia e a Tecnologia

Funda??o e Ci?ncia

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.1c00589

Reference42 articles.

1. World Health Organization. Leishmaniasis. http://www.who.int/leishmaniasis/en/ (accessed 2021-12-28).

2. World Health Organization. Control and surveillance of human African trypanosomiasis: Report of a WHO expert committee; World Health Organization: Geneva, 2013.

3. World Health Organization. World malaria report 2021; World Health Organization: Geneva, 2021.

4. Methods for assessment of antimalarial activity in the different phases of the Plasmodium life cycle

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