Discovery of a New Sulfonamide Hepatitis B Capsid Assembly Modulator-Reference-Cited by-同舟云学术

Discovery of a New Sulfonamide Hepatitis B Capsid Assembly Modulator

Published:2020-01-09 Issue:2 Volume:11 Page:166-171
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Na Hyo Gyeong¹²,Imran Ali¹,Kim Kyuneun¹²,Han Hong Sik¹²,Lee Young Jin¹²,Kim Myung-Jin³,Yun Chang-Soo¹,Jung Young-Sik¹²^ORCID,Lee Joo-Youn⁴,Han Soo Bong¹²^ORCID

Affiliation:

1. Bio and Drug Discovery Division, Korea Research Institute of Chemical Technology, PO Box 107, Daejeon 34114, Republic of Korea

2. Department of Medicinal Chemistry and Pharmacology, University of Science & Technology, Daejeon 34113, Republic of Korea

3. AM Sciences, C-912, SK V1 GL Metrocity, 128, Beobwon-ro, Songpa-gu, Seoul, 05854, Republic of Korea

4. Chemical Data-Driven Research Center, Korea Research Institute of Chemical Technology, 141 Gajeong-ro, Yuseong-gu, Daejeon 34114, Republic of Korea

Funder

Korea Research Institute of Chemical Technology

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.9b00550

Reference13 articles.

1. Modulators of HBV capsid assembly as an approach to treating hepatitis B virus infection

2. Preclinical Characterization of NVR 3-778, a First-in-Class Capsid Assembly Modulator against Hepatitis B Virus

3. Non-nucleoside anti-HBV agents: advances in structural optimization and mechanism of action investigations