<i>N</i>-Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–<i>Let-7</i> Interaction-Reference-Cited by-同舟云学术

N-Biphenyl Pyrrolinones and Dibenzofurans as RNA-Binding Protein LIN28 Inhibitors Disrupting the LIN28–Let-7 Interaction

Published:2023-11-14 Issue:12 Volume:14 Page:1707-1715
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Borgelt Lydia¹²³,Hohnen Lisa¹²⁴,Pallesen Jakob S.⁵^ORCID,Hommen Pascal¹²³,Goebel Georg L.¹²³,Bosica Francesco⁵,Liu Yang¹²³^ORCID,O’Mahony Gavin⁵^ORCID,Wu Peng¹²^ORCID

Affiliation:

1. Chemical Genomics Centre, Max Planck Institute of Molecular Physiology, Otto-Hahn Str. 15, Dortmund 44227, Germany

2. Department of Chemical Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn Str. 11, Dortmund 44227, Germany

3. Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn Str. 6, Dortmund 44227, Germany

4. Faculty of Chemistry and Biochemistry, Ruhr-University Bochum, Universitätsstr. 150, Bochum 44801, Germany

5. Medicinal Chemistry, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, SE-431 83 Mölndal, Sweden

Funder

Merck KGaA

AstraZeneca M?lndal

Pfizer

Max-Planck-Gesellschaft

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.3c00341

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