De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease-Reference-Cited by-同舟云学术

De Novo Discovery of Nonstandard Macrocyclic Peptides as Noncompetitive Inhibitors of the Zika Virus NS2B-NS3 Protease

Published:2019-01-04 Issue:2 Volume:10 Page:168-174
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Nitsche Christoph¹^ORCID,Passioura Toby²^ORCID,Varava Paul²,Mahawaththa Mithun C.¹,Leuthold Mila M.³,Klein Christian D.³^ORCID,Suga Hiroaki²^ORCID,Otting Gottfried¹^ORCID

Affiliation:

1. Research School of Chemistry, Australian National University, Canberra, ACT 2601, Australia

2. Department of Chemistry, Graduate School of Science, The University of Tokyo, Tokyo 113-0033, Japan

3. Medicinal Chemistry, Institute of Pharmacy and Molecular Biotechnology IPMB, Heidelberg University, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany

Funder

Core Research for Evolutional Science and Technology

Australian Research Council

Japan Science and Technology Agency

Alexander von Humboldt-Stiftung

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00535

Reference30 articles.