Application of Flow Photochemical Bromination in the Synthesis of a 5-Bromomethylpyrimidine Precursor of Rosuvastatin: Improvement of Productivity and Product Purity-Reference-Cited by-同舟云学术

Application of Flow Photochemical Bromination in the Synthesis of a 5-Bromomethylpyrimidine Precursor of Rosuvastatin: Improvement of Productivity and Product Purity

Published:2013-01-03 Issue:1 Volume:17 Page:145-151
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Šterk Damjan¹,Jukič Marko²,Časar Zdenko¹²³

Affiliation:

1. Sandoz Development Center Slovenia, API Development, Organic Synthesis Department, Lek Pharmaceuticals, d.d., Kolodvorska 27, 1234 Mengeš, Slovenia

2. Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000 Ljubljana, Slovenia

3. Global Portfolio Management API, Sandoz GmbH, Biochemiestrasse 10, 6250 Kundl, Austria

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/op300248y

Reference56 articles.

1. Structural Mechanism for Statin Inhibition of HMG-CoA Reductase

2. Historic Overview and Recent Advances in the Synthesis of Super-statins

3. Life after statin patent expiries

4. Lipid-lowering effects of statins: a comparative review

5. Synthesis and Biological Activity of Methanesulfonamide Pyrimidine- and N-Methanesulfonyl Pyrrole-Substituted 3,5-Dihydroxy-6-heptenoates, a Novel Series of HMG-CoA Reductase Inhibitors

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