Folate-Targeted Polymeric Nanoparticle Formulation of Docetaxel Is an Effective Molecularly Targeted Radiosensitizer with Efficacy Dependent on the Timing of Radiotherapy

Author:

Werner Michael E.12,Copp Jonathan A.12,Karve Shrirang12,Cummings Natalie D.12,Sukumar Rohit12,Li Chenxi3,Napier Mary E.4,Chen Ronald C.5,Cox Adrienne D.5,Wang Andrew Z.12

Affiliation:

1. Laboratory of Nano- and Translational Medicine, Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina−Chapel Hill, Chapel Hill, North Carolina, United States

2. Carolina Center for Cancer Nanotechnology Excellence, University of North Carolina−Chapel Hill, Chapel Hill, North Carolina, United States

3. Department of Biostatistics and NC TraCS Institute, University of North Carolina−Chapel Hill, Chapel Hill, North Carolina, United States

4. Department of Biochemistry and Biophysics, Lineberger Comprehensive Cancer Center, University of North Carolina−Chapel Hill, Chapel Hill, North Carolina, United States

5. Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina−Chapel Hill, Chapel Hill, North Carolina, United States.

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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