A 4‘-C-Ethynyl-2‘,3‘-Dideoxynucleoside Analogue Highlights the Role of the 3‘-OH in Anti-HIV Active 4‘-C-Ethynyl-2‘-deoxy Nucleosides-Reference-Cited by-同舟云学术

A 4‘-C-Ethynyl-2‘,3‘-Dideoxynucleoside Analogue Highlights the Role of the 3‘-OH in Anti-HIV Active 4‘-C-Ethynyl-2‘-deoxy Nucleosides

Published:2004-09-01 Issue:21 Volume:47 Page:5041-5048
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Siddiqui Maqbool A.¹,Hughes Stephen H.¹,Boyer Paul L.¹,Mitsuya Hiroaki¹,Van Que N.¹,George Clifford¹,Sarafinanos Stefan G.¹,Marquez Victor E.¹

Affiliation:

1. Laboratory of Medicinal Chemistry, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, HIV Drug Resistance Program, Center for Cancer Research, NCI-Frederick, NIH, Frederick, Maryland 21702, Experimental Retrovirology Section, Center for Cancer Research, NCI, NIH, Bethesda, Maryland 20892, NMR Group, Laboratory of Proteomics and Analytical Technologies, SAIC Frederick, Frederick, Maryland 21702, Laboratory for the Structure of Matter, Naval Research Laboratory, Washington, D.C....

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm049550o

Reference21 articles.

1. Syntheses of 4‘-C-Ethynyl-β-d-arabino- and 4‘-C-Ethynyl-2‘-deoxy-β-d-ribo-pentofuranosylpyrimidines and -purines and Evaluation of Their Anti-HIV Activity

2. 4′-Ethynyl Nucleoside Analogs: Potent Inhibitors of Multidrug-Resistant Human Immunodeficiency Virus Variants In Vitro

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