Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo

Author:

Mangraviti Antonella1,Tzeng Stephany Yi23,Kozielski Kristen Lynn23,Wang Yuan14,Jin Yike1,Gullotti David1,Pedone Mariangela1,Buaron Nitsa15,Liu Ann1,Wilson David R.23,Hansen Sarah K.23,Rodriguez Fausto J.6,Gao Guo-Dong4,DiMeco Francesco17,Brem Henry1289,Olivi Alessandro19,Tyler Betty1,Green Jordan J.123810

Affiliation:

1. Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States

2. Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States

3. The Institute for Nanobiotechnology and the Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States

4. Department of Neurosurgery, Tangdu Hospital, The Fourth Military Medical University, Xi’an 710032, China

5. Department of Chemical Engineering, Ben Gurion University of the Negev, Be’er Sheva 84105, Israel

6. Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States

7. Department of Neurosurgery, Fondazione IRCCS Istituto Neurologico C. Besta, Milan 20133, Italy

8. Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States

9. Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, United States

10. Department of Material Science and Engineering, Johns Hopkins University, Baltimore, Maryland 21231, United States

Funder

National Science Foundation

National Cancer Institute

National Institute of Biomedical Imaging and Bioengineering

Publisher

American Chemical Society (ACS)

Subject

General Physics and Astronomy,General Engineering,General Materials Science

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