Powerful Anticolon Tumor Effect of Targeted Gene Immunotherapy Using Folate-Modified Nanoparticle Delivery of CCL19 To Activate the Immune System

Author:

Liu Xiaoxiao12,Wang Bilan3,Li Yanyan14,Hu Yuzhu1,Li Xiaoling1,Yu Ting1,Ju Yan1,Sun Tao5,Gao Xiang16ORCID,Wei Yuquan1

Affiliation:

1. Department of Neurosurgery and Institute of Neurosurgery, State Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, West China Medical School, Sichuan University, Chengdu, 610041, PR China

2. Department of Radiation Oncology, Cancer Center, Affiliated Hospital of Xuzhou Medical University; Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical University, Xuzhou, 221000, China

3. Department of Pharmacy, West China Second University Hospital of Sichuan University, Chengdu, 610041, PR China

4. Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China

5. Key Laboratory of Smart Drug Delivery of Ministry of Education, State Key Laboratory of Medical Neurobiology, Department of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai 200032, PR China

6. West China School of Basic Medical Sciences & Forensic Medicine, Sichuan University, Chengdu 610041, PR China

Funder

Ministry of Science and Technology of Republic of China

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

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