From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase-Reference-Cited by-同舟云学术

From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase

Published:2018-11-14 Issue:23 Volume:20 Page:7488-7492
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Lu Dan¹,Zhu Sha¹,Sobala Lukasz F.²,Bernardo-Seisdedos Ganeko,Millet Oscar,Zhang Yongmin¹,Jiménez-Barbero Jesus³^ORCID,Davies Gideon J.²^ORCID,Sollogoub Matthieu¹^ORCID

Affiliation:

1. Sorbonne Université, CNRS, Institut Parisien de Chimie Moléculaire, UMR 8232, 4 place Jussieu, 75005 Paris, France

2. York Structural Biology Laboratory, Department of Chemistry, University of York, York YO10 5DD, U.K.

3. Ikerbasque, Basque Foundation for Science, Maria Diaz de Haro 3, 48013 Bilbao, Spain

Funder

China Scholarship Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.orglett.8b03260

Reference41 articles.

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2. The carbohydrate-active enzymes database (CAZy) in 2013

3. O-GlcNAcase Uses Substrate-assisted Catalysis

4. Mechanistic insights into glycosidase chemistry

5. Molecular Basis for Inhibition of GH84 Glycoside Hydrolases by Substituted Azepanes: Conformational Flexibility Enables Probing of Substrate Distortion

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