Stereocontrol of C–N Axial and Spiro-Central Chirality via Rh(II)-Catalyzed Enantioselective N–H Bond Insertion of Indolinone-Spiroacetal

Author:

Ren Qiao12ORCID,Lang Ming13,Liu Haitao4,Li Xiangyu1,Wu Daoshun1,Wu Jiayun5,Yang Meihua4,Wei Jianhe14,Ren Zhi5ORCID,Wang Lei14ORCID

Affiliation:

1. Institute of Medicinal Plant Development, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100193, China

2. College of Pharmaceutical Science, Southwest University, Chongqing 400715, China

3. School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China

4. Hainan Branch of the Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Haikou, Hainan 570311, China

5. College of Pharmacy, Shenzhen Technology University, Shenzhen 518118, China

Funder

Chongqing Research Program of Basic Research and Frontier Technology

Shenzhen Technology University

Hainan Provincial Department of Science and Technology

Chinese Academy of Medical Sciences

Jilin Province

Key Laboratory of Biotechnology and Bioresources Utilization, Ministry of Education

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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