BCX-1812 (RWJ-270201): Discovery of a Novel, Highly Potent, Orally Active, and Selective Influenza Neuraminidase Inhibitor through Structure-Based Drug Design
Author:
Affiliation:
1. BioCryst Pharmaceuticals, Inc., 2190 Parkway Lake Drive, Birmingham, Alabama 35244, and John Curtin School of Medical Research, Australian National University, Canberra 2601, Australia
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0002679
Reference16 articles.
1. SERIOUS MORBIDITY AND MORTALITY ASSOCIATED WITH INFLUENZA EPIDEMICS
2. Clinical and epidemiological importance of influenza a viruses resistant to amantadine and rimantadine
3. Protection against lethal influenza with neuraminidase
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