Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review

Author:

Simon Levente L.1,Pataki Hajnalka2,Marosi György2,Meemken Fabian3,Hungerbühler Konrad3,Baiker Alfons3,Tummala Srinivas4,Glennon Brian56,Kuentz Martin7,Steele Gerry8,Kramer Herman J. M.9,Rydzak James W.10,Chen Zengping11,Morris Julian12,Kjell Francois13,Singh Ravendra14,Gani Rafiqul14,Gernaey Krist V.14,Louhi-Kultanen Marjatta15,O’Reilly John16,Sandler Niklas17,Antikainen Osmo18,Yliruusi Jouko18,Frohberg Patrick19,Ulrich Joachim19,Braatz Richard D.20,Leyssens Tom21,von Stosch Moritz2223,Oliveira Rui2223,Tan Reginald B. H.2425,Wu Huiquan26,Khan Mansoor26,O’Grady Des27,Pandey Anjan27,Westra Remko28,Delle-Case Emmanuel29,Pape Detlef30,Angelosante Daniele30,Maret Yannick30,Steiger Olivier30,Lenner Miklós30,Abbou-Oucherif Kaoutar31,Nagy Zoltan K.3132,Litster James D.31,Kamaraju Vamsi Krishna525,Chiu Min-Sen25

Affiliation:

1. BASF Schweiz AG, 4133 Schweizerhalle, Switzerland

2. Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Műegyetem rkp. 3, H-1111 Budapest, Hungary

3. Department of Chemistry and Applied Biosciences, ETH Zürich, Vladimir-Prelog-Weg 1, 8093 Zürich, Switzerland

4. Chemical Development, Bristol-Myers Squibb Company, One Squibb Dr, New Brunswick, New Jersey 08903, United States

5. Synthesis and Solid State Pharmaceutical Centre, School of Chemical and Bioprocess Engineering, University College Dublin, Belfield, Dublin 4, Ireland

6. APC Ltd, Belfield Innovation Park, Dublin 4, Ireland

7. School of Life Sciences, Institute of Pharma Technology, University of Applied Sciences and Arts Northwestern Switzerland, Gründenstrasse 40, 4132 Muttenz, Switzerland

8. PharmaCryst Consulting Ltd., Loughborough, Leicestershire LE11 3HN, U.K.

9. Intensified Reaction & Separation Systems, Delft University of Technology, Leeghwaterstraat 39, 2628 CB Delft, The Netherlands

10. GlaxoSmithKline Pharmaceuticals, 709 Swedeland Rd, King of Prussia, Pennsylvania 19406, United States

11. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, PR China

12. Centre for Process Analytics & Control Technology, School of Chemical Engineering & Advanced Materials, Newcastle University, Newcastle upon Tyne, Tyne and Wear NE17RU, U.K.

13. Siemens nv/sa, Industry Automation − SIPAT Industry Software, Marie Curie Square 30, 1070 Brussels, Belgium

14. CAPEC-PROCESS, Department of Chemical and Biochemical Engineering, Technical University of Denmark (DTU), Building 229, DK-2800 Lyngby, Denmark

15. Department of Chemical Technology, Lappeenranta University of Technology, P.O. Box 20, FI-53851 Lappeenranta, Finland

16. Roche Ireland Limited, Clarecastle, Co. Clare, Ireland

17. Pharmaceutical Sciences Laboratory, Department of Biosciences, Abo Akademi University, Artillerigatan 6, 20520 Turku, Finland

18. Division of Pharmaceutical Technology, Faculty of Pharmacy, University of Helsinki, Yliopistonkatu 4, 00100 Helsinki, Finland

19. Center of Engineering Science, Thermal Process Engineering, Martin Luther University Halle-Wittenberg, D-06099 Halle (Saale), Germany

20. Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139, United States

21. Institute of Condensed Matter and Nanosciences, Université Catholique de Louvain, Place Louis Pasteur 1, 1348 Louvain-la-Neuve, Belgium

22. REQUIMTE - Departamento de Química, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, 1099-085 Caparica, Portugal

23. HybPAT, Caparica, Portugal

24. Institute of Chemical and Engineering Sciences, A*Star, 1 Pesek Road, Singapore 627833

25. Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576

26. Division of Product Quality Research, Office of Testing and Research, Office of Pharmaceutical Science, Center for Drug Evaluation and Research, US Food and Drug Administration (FDA), Silver Spring, Maryland 20993, United States

27. Mettler Toledo AutoChem, 7075 Samuel Morse Drive, Columbia, Maryland 20146, United States

28. FMC Technologies B.V., Delta 101, 6825 MN Arnhem, The Netherlands

29. University of Tulsa, 800 South Tucker Drive, Tulsa, Oklahoma 74104, United States

30. ABB Corporate Research Center, Segelhofstrasse 1K, 5405, Dättwil, Baden, Switzerland

31. School of Chemical Engineering, Purdue University, West Lafayette, Indiana 47906, United States

32. Chemical Engineering Department, Loughborough University, Loughborough, LE11 3TU, U.K.

Funder

Engineering and Physical Sciences Research Council

European Research Council

Ministry of Education of the People's Republic of China

Suomen Akatemia

National Natural Science Foundation of China

DTI

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

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