1. Laboratory of Nanomedicine and Biomaterials, Department of Anesthesiology, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts 02115, MIT-Harvard Center for Cancer Nanotechnology Excellence, Harvard-MIT Division of Health Sciences and Technology, Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, and National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892