Rational Use of Plasma Protein and Tissue Binding Data in Drug Design
Author:
Affiliation:
1. Genentech, Inc., South San Francisco, California 94080, United States
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm5007935
Reference64 articles.
1. Fast Gradient HPLC Method to Determine Compounds Binding to Human Serum Albumin. Relationships with Octanol/Water and Immobilized Artificial Membrane Lipophilicity
2. Plasma Protein Binding Affinity and Its Relationship to Molecular Structure: An In-silico Analysis
3. The importance of plasma protein binding in drug discovery
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