Optical Coherence Tomography Based Differentiation of Intravitreal Particles in Posterior Uveitis and Vitreous Hemorrhage

Abstract

Purpose: to study optical coherence tomography (OCT) characteristics of intravitreal particles in vitreous hemorrhage and posterior uveitis. Patients and methods. 29 patients with posterior uveitis (43.1 ± 19.4 years, 10 females and 19 males) and 29 patients with vitreous hemorrhage (62.3 ± 11.6 years, 9 females and 20 males) were included. All patients received standard ophthalmological examination and multimodal imaging, including OCT. The size and reflectivity of preretinal intravitreal particles was assessed on crosssectional OCT scans. Results: Intravitreal particles in eyes with posterior uveitis had a statistically significantly larger size compared to the particles in vitreous hemorrhage, 47.0 ± 29.0 and 41.3 ± 22.6 pixels, respectively (p < 0.001). At the same time, intravitreal particles in eyes with posterior uveitis had lower mean reflectivity compared with eyes with vitreous hemorrhage, 126.0 ± 10.5 and 135.2 ± 11.1, respectively (p < 0.001). The maximum reflectivity of intravitreal particles in eyes with posterior uveitis was also lower than that of particles in eyes with vitreous hemorrhage, 186.2 ± 24.9 and 166.3 ± 23.7, respectively (p < 0.001). Conclusion. Intravitreal particles displayed with OCT in posterior uveitis are less reflective and larger than those in vitreous hemorrhage.