The isolation of some hitherto undescribed products of hydrolysis of proteins. —Part II

Abstract

The main object of the investigations described in this paper was the further development of the “carbamate process” for the separation of the hydrolysis products of proteins, already described by the authors, and applied to the separation of the hydrolysis products of gelatin by Miss H. L. Kingston and Schryver. It has been shown that, by this method, the hydrolysis products can be fractionated into the following main groups:— I. Those products yielding barium salts insoluble in 70 per cent, alcohol; they consist entirely of dicarboxylic amino-acids. II. Those products yielding barium carbamates insoluble in ice-cold water. Two products only have, up to the present, been found in this fraction, viz., glycine, and a base, hydroxylysine, isolated for the first time by the authors in conjunction with Dr. D. H. Mukherjee.