The future of zoonotic risk prediction

Author:

Carlson Colin J.12ORCID,Farrell Maxwell J.3ORCID,Grange Zoe4,Han Barbara A.5ORCID,Mollentze Nardus67,Phelan Alexandra L.18,Rasmussen Angela L.1,Albery Gregory F.9,Bett Bernard10,Brett-Major David M.11ORCID,Cohen Lily E.12,Dallas Tad13ORCID,Eskew Evan A.14ORCID,Fagre Anna C.15ORCID,Forbes Kristian M.16ORCID,Gibb Rory1718ORCID,Halabi Sam8,Hammer Charlotte C.19ORCID,Katz Rebecca1,Kindrachuk Jason20,Muylaert Renata L.21,Nutter Felicia B.2223,Ogola Joseph24,Olival Kevin J.25,Rourke Michelle26,Ryan Sadie J.2728ORCID,Ross Noam25,Seifert Stephanie N.29,Sironen Tarja3031,Standley Claire J.12,Taylor Kishana32,Venter Marietjie33,Webala Paul W.34

Affiliation:

1. Center for Global Health Science and Security, Georgetown University Medical Center, Washington, DC 20007, USA

2. Department of Microbiology and Immunology, Georgetown University Medical Center, Washington, DC 20007, USA

3. Department of Ecology and Evolutionary Biology, University of Toronto, Toronto, Ontario, Canada

4. Public Health Scotland, Glasgow G2 6QE, UK

5. Cary Institute of Ecosystem Studies, Millbrook, NY 12545, USA

6. Medical Research Council, University of Glasgow Centre for Virus Research, Glasgow G61 1QH, UK

7. Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK

8. O'Neill Institute for National and Global Health Law, Georgetown University Law Center, Washington, DC 20001, USA

9. Department of Biology, Georgetown University, Washington, DC 20007, USA

10. Animal and Human Health Program, International Livestock Research Institute, PO Box 30709-00100, Nairobi, Kenya

11. Department of Epidemiology, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USA

12. Icahn School of Medicine at Mount Sinai, New York, NY, USA

13. Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70806, USA

14. Department of Biology, Pacific Lutheran University, Tacoma, WA, USA

15. Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA

16. Department of Biological Sciences, University of Arkansas, Fayetteville, AR 72701, USA

17. Centre on Climate Change and Planetary Health, London School of Hygiene and Tropical Medicine, London, UK

18. Centre for Mathematical Modelling of Infectious Diseases, London School of Hygiene and Tropical Medicine, London, UK

19. Centre for the Study of Existential Risk, University of Cambridge, Cambridge, UK

20. Department of Medical Microbiology and Infectious Diseases, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0J9

21. Molecular Epidemiology and Public Health Laboratory, Hopkirk Research Institute, Massey University, Palmerston North, New Zealand

22. Department of Infectious Disease and Global Health, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536, USA

23. Department of Public Health and Community Medicine, School of Medicine, Tufts University, Boston, MA 02111, USA

24. University of Nairobi, Nairobi, Kenya

25. EcoHealth Alliance, New York, NY 10018, USA

26. Law Futures Centre, Griffith Law School, Griffith University, Nathan, Queensland 4111, Australia

27. Department of Geography and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA

28. School of Life Sciences, University of KwaZulu-Natal, Durban, South Africa

29. Paul G. Allen School for Global Health, Washington State University, Pullman, WA, USA

30. Department of Virology, University of Helsinki, Helsinki, Finland

31. Department of Veterinary Biosciences, University of Helsinki, Helsinki, Finland

32. Department of Chemical Engineering, Carnegie Mellon University, Pittsburgh, PA 15213, USA

33. Zoonotic Arbo and Respiratory Virus Program, Centre for Viral Zoonoses, Department of Medical Virology, University of Pretoria, Pretoria, South Africa

34. Department of Forestry and Wildlife Management, Maasai Mara University, Narok 20500, Kenya

Abstract

In the light of the urgency raised by the COVID-19 pandemic, global investment in wildlife virology is likely to increase, and new surveillance programmes will identify hundreds of novel viruses that might someday pose a threat to humans. To support the extensive task of laboratory characterization, scientists may increasingly rely on data-driven rubrics or machine learning models that learn from known zoonoses to identify which animal pathogens could someday pose a threat to global health. We synthesize the findings of an interdisciplinary workshop on zoonotic risk technologies to answer the following questions. What are the prerequisites, in terms of open data, equity and interdisciplinary collaboration, to the development and application of those tools? What effect could the technology have on global health? Who would control that technology, who would have access to it and who would benefit from it? Would it improve pandemic prevention? Could it create new challenges? This article is part of the theme issue ‘Infectious disease macroecology: parasite diversity and dynamics across the globe’.

Funder

Wellcome Trust

Directorate for Biological Sciences

University of Toronto

Publisher

The Royal Society

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

Reference107 articles.

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