Affiliation:
1. Department of Respiratory Medicine, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, 310005, China
Abstract
The separation and identification of bioactive substances that come from natural resources have aroused increasing attention. Momordica charantia (M. charantia) has a variety of bio-activities, containing anti-oxidation, immune regulation, anti-tumor, radiation protection,
anti-diabetes, and liver protection. After the extraction new substances from Momordica charantia, their treatment effect on lung cancer combined with Hedyotis diffusa was determined and the related mechanism was explored as well in this study. Firstly, the CCK-8 assay was conducted
and the inhibition of the new substances combined with Hedyotis diffusa. Next, the real time RT-PCR was conducted and the relative expression of the VEGF in the cancer cells was determined. In addition, the complete chloroplast genome sequence of M. charantia is followed by the
phylogenetic analysis.
Publisher
American Scientific Publishers
Subject
Renewable Energy, Sustainability and the Environment,Biomaterials,Bioengineering
Reference25 articles.
1. Lung cancer in never smokers;Rivera;Advances in Experimental Medicine and Biology,2016
2. Diagnosis and molecular classification of lung cancer;Rodriguez-Canales;Cancer Treatment and Research,2016
3. Lung cancer in China: Current and prospect;Wu;Current Opinion Oncology,2021
4. Relationship between vascular endothelial growth factor −2578C> a gene polymorphism and lung cancer risk: A metaanalysis;Zhao;BMC Medical Genetics,2020
5. Is the vascular-endothelial growth factor responsible for the malignancy of lung cancer?;Rogoziński;Polski Merkuriusz Lekarski,2012