Author:
Shvaiko L. I., ,Bazyka K. D.,Shilenko M. V.,Olifer P. V.,Tkachuk N. A., , , ,
Abstract
The objective of the study was to establish the relationship between functional status of bronchopulmonary system and obstructive sleep apnea in clean-up workers of Chornobyl NPP accident in a remote post-accident period. Materials and methods. We included 58 COPD male patients clean-up workers of Chornobyl NPP accident: 21 with obstructive sleep apnea syndrome (OSA), 37 – without. A complex of functional tests and OSA screening was provided. Results. In clean-up workers of Chornobyl NPP accident with COPD and obstructive sleep apnea in a remote postaccident period apnea–hypopnea index (AHI) negatively correlated with FVC, % of predicted (r = -0.36, p < 0.05), the intrathoracic gas volume (ITGV), % of predicted (r = -0.40, p < 0.05); AHI positively correlated with diffusion lung capacity (DLCO), % of predicted values (r = 0.57, p < 0.05), with the intrathoracic gas volume (ITGV), % of predicted (r = 0.53, p < 0.05), body mass index (r = 0.49, p < 0.05) and age (r = 0.62, p < 0.05). Conclusions. Obstructive sleep apnea was diagnosed in 36.3 % of patients with COPD clean up workers of Chornobyl NPP accident. Screening for OSA in patients with COPD, clean-up workers of Chornobyl NPP accident is a very important clinical task for prognosis and treatment Key words: clean-up workers of Chornobyl NPP accident, pulmonary function tests, obstructive sleep apnea.
Publisher
National Research Center for Radiation Medicine of the NAMS of Ukraine
Subject
Radiology, Nuclear Medicine and imaging
Reference17 articles.
1. 1. Global Initiative for Chronic Obstructive Lung Disease. Global initiative for chronic obstructive lung disease global strategy for the diagnosis, management and prevention of COPD. Revised 2023 [Internet]. Available from: https://goldcopd.org/2024-gold-report/.
2. Сhronic obstructive pulmonary disease in the clean-up workers of Chornobyl npp accident in a remote post-accident period (clinical study);Shvaiko;Probl Radiac Med Radiobiol,2018
3. 3. Sushko VA, Nechaev S, Shvayko LI, et al. [Bronchopulmonary system]. In: Serdiuk AM, Bebeshko VG, Bazyka DA, editors. [Medical consequences of the Chornobyl catastrophe: 1986-2011]. Ternopil: TDMU, Ukrmedknyha; 2011. p. 460-506. Ukrainian.
4. 4. Sushko V, Shvaiko L, Bazyka K, et al. [The state of respiratory system in clean-up workers of the Chornobyl accident: results of thirty year study]. Journal of the NAMS of Ukraine. 2016;(2):193-197. Ukrainian.
5. Comorbidome, pattern, and impact of asthma-COPD overlap syndrome in real life;van Boven;Chest,2016