Evaluation of Cases Diagnosed with Gestational Trophoblastic Disease

Abstract

Objective: The aim of our study is to discuss the incidence, demographic characteristics, possible complications, follow-up and treatment approaches of patients diagnosed with gestational trophoblastic disease (GTH) with current literature. Materials and Methods: 134 patients who were diagnosed with GTD histopathologically in our clinic between 2005 and 2020 were included in the study retrospectively. Application complaints, demographic data, laboratory tests, treatments, presence of other comorbidities, transfusion and chemotherapy needs of these patients were evaluated. Partial and complete molar hydatiform pregnancies were compared with each other. Results: The diagnosis of GTD was made at an average of 8 weeks. The mean age of the patients was 29.9±7.49 years. According to the histopathological results, 91 (67.9%) patients with partial mole and 37 (27.6%) patients with complete mole were found. Invasive mole was detected in one patient (0.7%), choriocarcinoma in one patient (0.7%), and placental trophoblastic tumor (PSTT) in one patient (0.7%). In GTD patients, A Rh(+) blood group was the most, B Rh(-) and AB Rh(-) blood groups were the least. Conclusion: Early diagnosis and appropriate follow-up-treatment in GTD patients are extremely important and play a critical role in preventing disease-related morbidity and mortality.