The significance of CO2 combining power in predicting prognosis of patients with stage II and III colorectal cancer-Reference-Cited by-同舟云学术

The significance of CO2 combining power in predicting prognosis of patients with stage II and III colorectal cancer

Published:2019-09 Issue:13 Volume:13 Page:1071-1080
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Li Sheng¹,Zhu Liangjun¹,Cheng Xianfeng²,Wang Qianyu³,Feng Jifeng¹,Zhou Jianwei⁴

Affiliation:

1. Department of Medical Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, No.42, Baiziting, Nanjing 210009, Jiangsu Province, PR China

2. Clinic laboratory of Institute of Dermatology & Hospital for Skin Diseases, Chinese Academy of Medical Sciences, No.12, Jiangwangmiao Street, Xuanwu District, Nanjing 210042, Jiangsu Province, PR China

3. Department of Pathology, Suqian First Hospital, No. 120, Suzhi Road, Sucheng District, Suqian 223899, Jiangsu Province, PR China

4. Department of Molecular Cell Biology & Toxicology, Key Laboratory of Modern Toxicology of the Ministry of Education, School of Public Health, Nanjing Medical University, 101 Longmian Avenue, Jiangning Distric, Nanjing 211166, Jiangsu Province, PR China

Abstract

Aim: This study was to evaluate whether CO2CP level in venous blood could predict prognosis of patients with colorectal cancer (CRC). Materials & methods: A retrospective cohort of 238 patients with CRC who received surgical resection and 176 CRC Stage IV patients were included. A total of 114 healthy people were recruited as control. CO2CP levels were obtained from medical records. Survival analysis was performed to evaluate CO2CP predictive potential. The patients were divided into CO2CP high or low group based on CO2CP optimal cut-off values. Conclusion: The decreased CO2CP in CRC patients was associated with advanced clinical stage, and suggested that decreased CO2CP may predict the worse outcomes of disease-free survival in II/III stage CRC patients.

Publisher

Future Medicine Ltd

Subject

Biochemistry, medical,Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2018-0321

Reference35 articles.

1. Overweight is associated to a better prognosis in metastatic colorectal cancer: A pooled analysis of FFCD trials

2. From colorectal to general surgeon in the management of left colonic perforation: A cohort study

3. Metastatic Colorectal Cancer: Current State and Future Directions

4. Relationship among circulating tumor cells, CEA and overall survival in patients with metastatic colorectal cancer

5. Associations Between Molecular Classifications of Colorectal Cancer and Patient Survival: A Systematic Review

Cited by 9 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Incidence and associated factors for hypotension during continuous renal replacement therapy in critically ill patients;International Journal of Nursing Practice;2024-07-29

2. Development and validation of a prognostic nomogram for predicting in-hospital mortality of patients with acute paraquat poisoning;Scientific Reports;2024-01-18

3. Expression levels and diagnostic value of serum GDNF, CEA and CA199 in patients with Colorectal Carcinoma;Journal of Medical Biochemistry;2023-10-03

4. Predictive value of admission CO2 combining power combined with serum sodium for the prognosis in acute Stanford type A aortic dissection patients;Scientific Reports;2023-01-19

5. Carbon-dioxide-combining-power and postoperative short-term mortality in patients with Stanford type A acute aortic dissection;Asian Journal of Surgery;2022-12