Recent advances in electrospun nanofibers for wound healing

Author:

Chen Shixuan1,Liu Bing12,Carlson Mark A34,Gombart Adrian F5,Reilly Debra A6,Xie Jingwei1

Affiliation:

1. Department of Surgery–Transplant & Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE 68198, USA

2. Department of Anorectal Surgery, The First Affiliated Hospital of China Medical University, Shenyang, Liaoning 110001, China

3. Departments of Surgery & Genetics, Cell Biology & Anatomy, University of Nebraska Medical Center, Omaha, NE 68198, USA

4. Department of Surgery, VA Nebraska–Western Iowa Health Care System, Omaha, NE 68105, USA

5. Department of Biochemistry & Biophysics & Linus Pauling Institute, Oregon State University, Corvallis, OR 97331, USA

6. Departments of Surgery–Plastic & Reconstructive Surgery, University of Nebraska Medical Center, Omaha, NE 68198, USA

Abstract

Electrospun nanofibers represent a novel class of materials that show great potential in many biomedical applications including biosensing, regenerative medicine, tissue engineering, drug delivery and wound healing. In this work, we review recent advances in electrospun nanofibers for wound healing. This article begins with a brief introduction on the wound, and then discusses the unique features of electrospun nanofibers critical for wound healing. It further highlights recent studies that have used electrospun nanofibers for wound healing applications and devices, including sutures, multifunctional dressings, dermal substitutes, engineered epidermis and full-thickness skin regeneration. Finally, we finish with conclusions and future perspective in this field.

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

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