Mending the gaps: ethically sensitive cells and the evolution of European stem cell policy

Author:

Rosario  Isasi 1,Ginoza Margaret2ORCID,Jongsma Karin3ORCID,Lars Assen 3ORCID,Morris Fabbri 4

Affiliation:

1. Dr John T Macdonald Foundation Department of Human Genetics, John P. Hussman Institute for Human Genomics, Interdisciplinary Stem Cell Institute

2. University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA

3. University Medical Center Utrecht, Utrecht, NL 3584

4. Dr John T Macdonald Foundation Department of Human Genetics, John P. Hussman Institute for Human Genomics, University of Miami Leonard M. Miller School of Medicine, Miami, FL 33136, USA

Abstract

The past decades witnessed the slow evolution of Europe's heterogeneous stem cell (SC) policy and substantial scientific advances in the field. Parallel to these developments, professional organizations have grown in influence. With the recently revised International Society for Stem Cell Research's Guidelines as a backdrop, we address the evolution of SC policies in 46 European countries and discuss how they fare against evolving ethical standards, societal views, and scientific advances. We identify areas of convergence, divergence, and the suitability of extant governance mechanisms to meet their stewardship roles. Europe represents a rich case study as it encompasses a wide range of policy approaches present worldwide. Comparative studies provide an opportunity to promote insight into national frameworks and to foster international harmonization.

Funder

Horizon 2020 research and innovation program

Publisher

Future Medicine Ltd

Subject

Embryology,Biomedical Engineering

Reference108 articles.

1. International Society for Stem Cell Research (ISSCR). Guidelines for Stem Cell Research and Clinical Translation (2021). www.isscr.org/docs/default-source/all-isscr-guidelines/2021-guidelines/isscr-guidelines-for-stem-cell-research-and-clinical-translation-2021.pdf?sfvrsn=979d58b1_4

2. ISSCR guidelines fudge heritable human-genome editing

3. Stein R. Controversial new guidelines would allow experiments on more mature human embryos. National Public Radio. (2021). www.npr.org/sections/health-shots/2021/05/26/1000126212/new-guidelines-would-allow-experiments-on-more-mature-human-embryos

4. European Commission. “Horizon Europe: research and innovation funding programme until 2027. How to get funding, programme structure, missions, European partnerships, news and events”. https://ec.europa.eu/info/research-and-innovation/funding/funding-opportunities/funding-programmes-and-open-calls/horizon-europe_en (Accessed 13 Dec. 2021).

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