Evaluation of a multi-slice spiral computed tomography perfusion for the prediction of the recurrence of gastric cancer

Author:

Li Chun-Feng1,Wang Da-Peng2,Xue Ying-Wei1

Affiliation:

1. First Gastrointestinal Surgical Ward, The Harbin Medical University Cancer Hospital, Harbin 150081, PR China

2. Human Resources Department, The Harbin Medical University Cancer Hospital, Harbin 150081, PR China

Abstract

Aim: The study aimed to elucidate the value of multislice spiral computed tomography (MSCT) perfusion for the early prediction of gastric cancer (GC) recurrence. Methods: MSCT perfusion scans were performed to obtain values pertaining to blood flow (BF), blood volume (BV), mean transit time (MTT) and permeability surface (PS). Logistic regression analysis was employed to evaluate the risk factors of postoperative recurrence in GC. Results: The maximum diameter of GC has a positive relationship with PS. The maximum enhancement of GC was positively correlated with BF, blood volume and PS. PS, BF, vascular thrombus and Tumor, Node, Metastasis staging were found to be significant risk factors in relation to the recurrence of GC (p = 0.006, p = 0.002, p < 0.001). Conclusion: MSCT perfusion is strongly correlated with postoperative recurrence of GC, and PS and BF values, vascular thrombus and Tumor, Node, Metastasis staging were discovered as being prominent factors influencing the recurrence of GC.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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