Evaluation of the effect of UGT1A1 polymorphisms on dolutegravir pharmacokinetics
Author:
Affiliation:
1. GlaxoSmithKline, Research Triangle Park, NC, USA
2. GlaxoSmithKline, Stevenage, Hertfordshire, UK
3. GlaxoSmithKline, Stevenage, Hertfordshire, UK.
Abstract
Publisher
Future Medicine Ltd
Subject
Pharmacology,Genetics,Molecular Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/pgs.13.190
Reference21 articles.
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3. Safety and Efficacy of Dolutegravir in Treatment-Experienced Subjects With Raltegravir-Resistant HIV Type 1 Infection: 24-Week Results of the VIKING Study
4. In Vitro Investigations into the Roles of Drug Transporters and Metabolizing Enzymes in the Disposition and Drug Interactions of Dolutegravir, a HIV Integrase Inhibitor
5. Antiviral activity, safety, and pharmacokinetics/pharmacodynamics of dolutegravir as 10-day monotherapy in HIV-1-infected adults
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