The application of nanotechnology in kidney transplantation

Author:

Li Shengzhou1,Chen Yiming2,Cao Xiangqian1,Yang Chenkai1,Li Wei3,Shen Bing14

Affiliation:

1. Department of Urology, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai, China

2. Department of Orthopedics, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080, Shanghai,China

3. Department of Nanomedicine & Shanghai Key Lab of Cell Engineering, Naval Medical University, 200433, Shanghai, China

4. Shanghai Tenth People’s Hospital of Tongji University, 200072, Shanghai, China

Abstract

Kidney transplantation is a crucial treatment option for end-stage renal disease patients, but challenges related to graft function, rejection and immunosuppressant side effects persist. This review highlights the potential of nanotechnology in addressing these challenges. Nanotechnology offers innovative solutions to enhance organ preservation, evaluate graft function, mitigate ischemia-reperfusion injury and improve drug delivery for immunosuppressants. The integration of nanotechnology holds promise for improving outcomes in kidney transplantation.

Funder

National Natural Science Foundation of China

Program of Shanghai Academic/Technology Research Leader

Shanghai Songjiang Municipal Science and Technology Commission Natural Science Foundation

University of Shanghai for Science and Technology

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

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