Circulating miRNAs in blood and urine as diagnostic and prognostic biomarkers for bladder cancer: an update in 2017-Reference-Cited by-同舟云学术

Circulating miRNAs in blood and urine as diagnostic and prognostic biomarkers for bladder cancer: an update in 2017

Published:2018-06 Issue:6 Volume:12 Page:667-676
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Tölle Angelika¹²,Blobel Conrad C¹,Jung Klaus³

Affiliation:

1. Department of Urology, Charité – Universitätsmedizin Berlin, 10117 Berlin, Germany

2. CONGEN Biotechnology GmbH, 13125 Berlin, Germany

3. Berlin Institute for Urologic Research, 10117 Berlin, Germany

Abstract

This study presents a critical appraisal of previously published study data of miRNAs in blood, urine and exosomes as biomarkers of bladder cancer (BC). The evaluation included 39 articles published from the beginning of 2010 until September 2017 and searched in PubMed. The heterogeneity of studies, due to their clinicopathological variability, including insufficient consideration of diagnostic and prognostic biomarker guidelines and missing internal and external validation of data, do not currently allow the recommending of a useful miRNA marker as diagnostic or prognostic tool in BC. Future multi-institutional studies are necessary to overcome the deficiencies in these studies in order to prove the usefulness of circulating miRNAs as robust biomarkers for BC.

Publisher

Future Medicine Ltd

Subject

Biochemistry, medical,Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2017-0392

Reference78 articles.

1. EAU Guidelines on Non–Muscle-invasive Urothelial Carcinoma of the Bladder: Update 2016

2. Updated 2016 EAU Guidelines on Muscle-invasive and Metastatic Bladder Cancer

3. Upper Urinary Tract Recurrence Following Radical Cystectomy for Bladder Cancer: A Meta-Analysis on 13,185 Patients

4. European Association of Urology Guidelines on Upper Urinary Tract Urothelial Cell Carcinoma: 2015 Update

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