Knowledge, attitudes and practice regarding pharmacovigilance and adverse drug reaction reporting among physicians and pharmacists in Egypt: a step toward personalized medicine implementation-Reference-Cited by-同舟云学术

Knowledge, attitudes and practice regarding pharmacovigilance and adverse drug reaction reporting among physicians and pharmacists in Egypt: a step toward personalized medicine implementation

Published:2022-11 Issue:6 Volume:19 Page:495-507
ISSN:1741-0541
Container-title:Personalized Medicine
language:en
Short-container-title:Personalized Medicine

Author:

Aziz Alaa Abdel¹²^ORCID,Rogers Sara³⁴⁵^ORCID,Hassanien Omneya⁶,Shalaby Lobna⁷⁸,Nagy Mohamed¹⁹^ORCID

Affiliation:

1. Department of Pharmaceutical Services, Children's Cancer Hospital Egypt, Cairo, 57357, Egypt

2. Department of Pharmacy, Ain Shams University Hospitals, Cairo, Egypt

3. American Society of Pharmacovigilance, Houston, TX 77225, USA

4. Department of Pharmacy Practice, Irma Lerma Rangel College of Pharmacy, Texas A&M Health Science Center, Kingsville, TX 78363, USA

5. Department of Translational Medical Sciences, College of Medicine, Texas A&M Health Science Center, Bryan, TX 77807, USA

6. Department of Epidemiology & Clinical Research, Children's Cancer Hospital Egypt, Cairo, 57357, Egypt

7. Infectious Disease Unit, Children's Cancer Hospital Egypt, Cairo, 57357, Egypt

8. Department of Pediatric Oncology, National Cancer Institute, Cairo University, Cairo, Egypt

9. Personalized Medication Management Unit, Children's Cancer Hospital Egypt, Cairo, 57357, Egypt

Abstract

Aim: To assess the knowledge, attitudes, and practices of the healthcare professionals working at Children's Cancer Hospital Egypt regarding pharmacovigilance (PV) and adverse drug reaction (ADR) reporting, in addition to the ADR reporting barriers. Materials & methods: A cross-sectional study was conducted at Children's Cancer Hospital Egypt from July to September 2021 using a validated questionnaire. Results: About 37 physicians (20.3%) and 145 pharmacists (79.7%) responded to the survey. Overall, the knowledge (median: 40%) and practice (median: 50%) of PV and the reporting of ADRs were low; however, attitudes were mostly positive. The main barrier to reporting ADRs was The difficulty of determining whether or not ADRs occurred (42.3%). Conclusion: Understanding of PV and ADR reporting could improve the huge gap between ADRs experienced and ADRs reported. In order to be able to assess the impact of personalized medicine implementation, adequate ADR reporting should be well established.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Molecular Medicine,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/pme-2022-0030

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