Real-world evidence research in metastatic colorectal cancer: raising awareness of the need for patient contributions

Author:

Moss Barbara1,Goodall Edward A2,Maravic Zorana1ORCID,Marti Francisca3,Moss Mark1,Rowley Stephen14,Sarrauste Cyril15,Wheatstone Pete6

Affiliation:

1. Digestive Cancers Europe, Rue de la Loi 235/27, 1040 Brussels, Belgium

2. Northern Ireland Cancer Research Consumer Forum, Belfast City Hospital, 51 Lisburn Road, Belfast, BT9 7AB, UK

3. Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester, M20 4BX, UK

4. Bowel Cancer Support Group UK

5. Mon Réseau Cancer Colorectal/Patients en Réseau, 15 Rue Gît le Coeur, 75006 Paris, France

6. DATA-CAN, c/o St. James University Hospital, Beckett Street, Leeds, LS9 7TF, UK

Abstract

Real-world evidence (RWE) research helps determine whether outcomes observed in clinical trials happen in real-life clinical practice. RWE research may help patients receive more appropriate treatment, closer to their needs and wishes. RWE for metastatic colorectal cancer is currently limited. The PROMETCO RWE study is an important example of an ongoing initiative that focuses on patient-reported outcomes in metastatic colorectal cancer. Patients play an active role throughout the RWE research process, including study design, participation and results dissemination. This involvement can encourage greater patient empowerment through active engagement, potentially resulting in various benefits that can lead to improved clinical outcomes. Greater patient engagement can increase involvement in RWE, helping more patients to access the benefits of RWE research. Clinical Trial Registration: NCT03935763 ( ClinicalTrials.gov )

Funder

Servier

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Reference78 articles.

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3. National Cancer Institute. Surveillance, Epidemiology, and End Results Program. Cancer stat facts: colorectal cancer (2022). Available at: https://seer.cancer.gov/statfacts/html/colorect.html (Accessed 27 September 2022).

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5. Global patterns and trends in colorectal cancer incidence in young adults

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