An action plan to address the rising burden of colorectal cancer in younger adults

Author:

Lowery Jan T1ORCID,Weber Thomas K2,Ahnen Dennis J3,Schroy III Paul C4,Levell Caleb L5,Smith Robert A5

Affiliation:

1. Center for Personalized Medicine, University of Colorado, Aurora, CO 80045, USA

2. Northwell Health, Professor of Surgery, Donald & Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY 10028, USA

3. Gastroenterology of the Rockies, University of Colorado School of Medicine & Director of Genetics Program, Aurora, CO 80045, USA

4. Boston University School of Medicine, Section of Gastroenterology, Boston, MA 02118, USA

5. American Cancer Society, Atlanta, GA 30303, USA

Abstract

Aim: The National Colorectal Cancer Roundtable convened a national Summit to discuss the causes of early-onset colorectal cancer and clinical challenges to mitigating burden of this disease. Materials & methods: Information presented was synthesized through scientific consensus building to determine priorities for new research and practice change. Results: Research priorities include evaluating role of novel risk factors, understanding natural history and identifying ways to implement evidenced-based practices for identifying and managing at-risk persons. Practice change should focus on adoption of guidelines for collecting family history, screening in young adults at risk, provider and population awareness about risk and symptoms, and universal tumor testing. Conclusion: Successful implementation of strategies to address research and practice change will require collaboration from multiple partners.

Publisher

Future Medicine Ltd

Subject

Gastroenterology,Oncology

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