Postmastectomy radiation therapy for breast cancer patients with one to three positive lymph nodes: a propensity score matching analysis-Reference-Cited by-同舟云学术

Postmastectomy radiation therapy for breast cancer patients with one to three positive lymph nodes: a propensity score matching analysis

Published:2017-07 Issue:16 Volume:13 Page:1395-1404
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Lin Jiamao¹,Li Cheng²,Zhang Chenyue³,Shi Fang⁴,Wang Haiyong⁴

Affiliation:

1. Department of Internal Medicine-Oncology, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan 250117, China

2. Dean's Office, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan 250117, China

3. Department of Integrative Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China

4. Department of Radiation Oncology, Shandong Cancer Hospital & Institute, Shandong Cancer Hospital Affiliated to Shandong University, Shandong Academy of Medical Sciences, Jinan 250117, China

Abstract

Aim: Conducting postmastectomy radiation therapy (PMRT) for breast cancer patients with one to three positive lymph nodes is still controversial. Methods: Propensity score matching analysis was applied to balance the clinical baseline characteristics of patients. Cox proportional hazard analysis was used to analyze the survival prognosis factors and perform subgroup analysis. Results: There was no statistical difference in overall survival and cancer-specific survival rates (all, p > 0.05) between the PMRT and non-PMRT groups. However, for subgroup patients with tumor size ≥5 cm and the number of positive lymph nodes = 3, PMRT showed a significant survival benefit. Conclusion: PMRT can improve overall survival and cancer-specific survival only in breast cancer patients whose tumor size is larger than 5 cm and with three positive lymph nodes.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon-2017-0099

Reference35 articles.

1. Postmastectomy Radiotherapy: Clinical Practice Guidelines of the American Society of Clinical Oncology*

2. Is the benefit of postmastectomy irradiation limited to patients with four or more positive nodes, as recommended in international consensus reports? A subgroup analysis of the DBCG 82 b&c randomized trials

3. ACR Appropriateness Criteria® on Postmastectomy Radiotherapy

4. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: an overview of the randomised trials

5. Should all breast cancer patients with four or more positive lymph nodes who underwent modified radical mastectomy be treated with postoperative radiotherapy? A population-based study

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