Diseases caused by nontuberculous mycobacteria in Asia

Author:

Lai Chih-Cheng1,Hsueh Po-Ren2

Affiliation:

1. Department of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Tainan, Taiwan

2. Department of Internal Medicine & Laboratory Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan.

Abstract

ABSTRACT: The isolation rate of nontuberculous mycobacteria (NTM) species and the prevalence of NTM-associated diseases are on the rise in Asian, as well as in Western countries; however, the species distribution of NTM isolates and the types of diseases caused by NTM species vary from region to region. In this review, we present an update on the epidemiology of NTM in Asia. We demonstrate that the distribution of NTM species varies within Asia and differs from that in North America and Europe. In addition, the clinical manifestations of NTM diseases include respiratory tract infections, disseminated infections, skin and soft tissue infections, lymphadenitis, empyema, ocular infections, CNS infections and genitourinary infections. Finally, the rate of adaptive resistance of anti-NTM antimicrobial agents remains high and may be associated with a poor outcome for patients with NTM diseases.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

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