Effects of opioid-reduced anesthesia during scoliosis surgery in children: a prospective observational study-Reference-Cited by-同舟云学术

Effects of opioid-reduced anesthesia during scoliosis surgery in children: a prospective observational study

Published:2021-11 Issue:6 Volume:11 Page:679-687
ISSN:1758-1869
Container-title:Pain Management
language:en
Short-container-title:Pain Management

Author:

Julien-Marsollier Florence¹²³,Assaker Rita¹²³,Michelet Daphné¹²³,Camby Matthieu¹²³,Galland Anne¹²³,Marsac Lucile¹²³,Vacher Thomas¹²³,Simon Anne-laure¹⁴,Ilharreborde Brice¹⁴,Dahmani Souhayl¹²³

Affiliation:

1. Université de Paris, Paris, France

2. Department of Anesthesia & Intensive Care, Robert Debré Hospital, 48 Boulevard Sérurier, 75019, Paris, France

3. DMU PROTECT, Robert Debré Hospital, 48 Boulevard Sérurier 75019, Paris, France

4. Department of Orthopedic Surgery, Robert Debré Hospital, 48 Boulevard Sérurier, 75019, Paris, France

Abstract

Aims: Opioid-reduced anesthesia (ORA) was suggested to decrease morphine consumption after adolescent idiopathic scoliosis (AIS) surgery and incidence of chronic pain. Materials & methods: A prospective analysis using the ORA in AIS surgery was performed. Two cohorts were compared: a control group (opioid-based anesthesia) and the ORA group. The main outcome was morphine consumption at day 1. Results: 33 patients operated for AIS using ORA were compared with 36 with opioid-based anesthesia. Morphine consumption was decreased in the ORA group (1.1 mg.kg-1 [0.2–2] vs 0.8 mg.kg-1 [0.3–2]; p = 0.02) at day 1. Persistent neuropathic pain at 1 year was decreased in the ORA group (p = 0.02). Conclusion: The ORA protocol is efficient to reduce postoperative morphine consumption in AIS surgery and preventing neuropathic pain.

Publisher

Future Medicine Ltd

Subject

General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/pmt-2020-0100

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