Nomogram for predicting prolonged postoperative ileus in colorectal cancer based on age and inflammatory markers

Author:

Fan Zong-Qi1,Chen Yang2,Fu Xin-Ao23,Yin Hao-Ting1,Li Ju-Shang23,Wang Wei-Si2,Yuan Jie-Qing2,Guo Shi-Gang1

Affiliation:

1. Department of Gastrointestinal Surgery, Chaoyang Central Hospital Postgraduate Training Base of Jinzhou Medical University, Liaoning Province, 122000, PR China

2. Department of Gastrointestinal Surgery, Chaoyang Central Hospital, Liaoning Province, 122000, PR China

3. China Medical University, Liaoning Province, 110000, PR China

Abstract

Aim: To explore the relationship between inflammatory markers and prolonged postoperative ileus (PPOI), and to establish a nomogram for predicting PPOI. Patients & methods: The data of 229 patients were analyzed retrospectively. Univariate and multivariate logistic regression analysis were used to analyze the risk factors affecting the occurrence of PPOI. The predictive model of PPOI was established and verified internally. Results: Postoperative PPOI occurred in 87 (38.0%) of all 229 patients. Our study showed that age, preoperative neutrophil–lymphocyte ratio and changes in neutrophil–lymphocyte ratio were independent risk factors for PPOI. Conclusion: The nomograms established based on these independent risk factors have good predictive efficacy and may be able to guide clinicians to individualize the diagnosis and treatment.

Funder

Chaoyang Central Hospital

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

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