Analysis of risk factors of lymph node metastasis in rectal neuroendocrine neoplasms using multicenter data-Reference-Cited by-同舟云学术

Analysis of risk factors of lymph node metastasis in rectal neuroendocrine neoplasms using multicenter data

Published:2018-08 Issue:18 Volume:14 Page:1817-1823
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Wei Gengzhou¹²,Feng Xingyu¹,Wang Wei³,Zhang Yu⁴,Zeng Yujie⁵,Chen Minhu⁴,Chen Ye⁶,Chen Jie⁴,Zhou Zhiwei³,Li Yong¹

Affiliation:

1. Department of General Surgery, Guangdong General Hospital; Guangdong Academy of Medical Sciences, Guangzhou, PR China

2. Department of Medical College, South China University of Technology, Ganzhou, PR China

3. Department of Gastric Surgery, Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China; Collaborative Innovation Center for Cancer Medicine, Guangzhou, PR China

4. Department of Gastroenterology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, PR China

5. Department of Gastrointestinal Surgery, Sun Yat-sen Memorial Hospital of Sun Yat-sen University, Guangzhou, PR China

6. Department of Gastroenterology, Nanfang Hospital of Southern Medical University; Guangdong Provincial Key Laboratory of Gastroenterology, Guangzhou, PR China

Abstract

Aim: This study was conducted to analyze the risk factors associated with lymph node metastasis in rectal neuroendocrine neoplasms (NENs). Materials & methods: A total of 419 patients with rectal NENs were enrolled. A univariate analysis of risk factors of lymph node metastasis was conducted using a χ2 test, and a multivariate analysis was conducted using a logistic regression analysis. Results: Univariate and multivariate regression analysis revealed that tumor size, G grade and the depth of tumor invasion were independent risk factors for lymph node metastasis (p < 0.05). Conclusion: Rectal NENs patients with a larger tumor size, deeper tumor invasion or a higher G grade had a higher risk of regional lymph node metastasis.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon-2018-0059

Reference17 articles.

1. One Hundred Years After “Carcinoid”: Epidemiology of and Prognostic Factors for Neuroendocrine Tumors in 35,825 Cases in the United States

2. Gastroenteropancreatic neuroendocrine tumours

3. The Epidemiology of Gastroenteropancreatic Neuroendocrine Tumors

4. A 5-decade analysis of 13,715 carcinoid tumors

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Lymph node ratio and hematological parameters predict relapse-free survival in patients with high grade rectal neuroendocrine neoplasms after radical resection: a multicenter prognostic study;World Journal of Surgical Oncology;2023-09-22

2. Lymph node ratio and hematological parameters predict relapse-free survival in Patients With high grade rectal neuroendocrine neoplasms after radical resection: A multicenter prognostic study;2023-07-03

3. Prognostic value of computed tomography radiomics features in patients with gastric neuroendocrine neoplasm;Frontiers in Oncology;2023-06-20

4. Survival in patients with neuroendocrine tumors of the colon, rectum and small intestine;The American Journal of Surgery;2023-01

5. A model based on endorectal ultrasonography predicts lateral lymph node metastasis in low and middle rectal cancer;Journal of Clinical Ultrasound;2022-03-24