L. plantarum and L. lactis as a promising agent in treatment of inflammatory bowel disease and colorectal cancer

Author:

Javid Hossein12ORCID,Oryani Mahsa Akbari3,Akbari Sanaz4,Amiriani Taghi5,Ravanbakhsh Samaneh6,Rezagholinejad Nastaran7,Afshari Amir-R8,Karimi-Shahri Mehdi39ORCID

Affiliation:

1. Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 1313199137, Iran

2. Department of Medical Laboratory Sciences, Varastegan Institute for Medical Sciences, Mashhad, 917966679, Iran

3. Department of Pathology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, 1313199137, Iran

4. Department of Biology, Islamic Azad University, Mashhad Branch, Mashhad, 9133736351, Iran

5. Golestan Research Center of Gastroenterology & Hepatology, Golestan University of Medical Sciences, Gorgan, 4918936316, Iran

6. Biology Expert, Plant Sciences, graduate of Golestan University, Gorgan, 4918936316, Iran

7. Department of Biochemistry, Payame Noor University (PNU), Mashhad, 193954697, Iran

8. Department of Physiology & Pharmacology, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, 9414974877, Iran

9. Department of Pathology, School of Medicine, Gonabad University of Medical Sciences, Gonabad, 9691657678, Iran

Abstract

It has been understood for nearly a century that patients with intestinal inflammatory disease (IBD) have a higher risk of developing colorectal cancer (CRC). Recently, two species of lactic acid bacteria, Lactobacillus plantarum and Lactococcus lactis, have been investigated as therapeutic agents for IBD. These bacteria have been shown to survive gastric transit, to adhere and colonize in the intestinal tract of humans and modulate the intestinal microbiota and immune response. L. plantarum and L. lactis might be used as multifunctional drugs for the treatment of IBD and the prevention or treatment of CRC. This article summarizes current knowledge of L. plantarum and L. lactis as therapeutic and preventative agents for IBD and CRC, respectively.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3