Fish collagen peptides' modulating effect on human skin microbiota against pathogenic Staphylococcus aureus

Author:

Bayan Rasol1,Tauseef Isfahan1,Hussain Mubashir2,Ahmed Muhammad S3ORCID,Haider Adnan3,Khalil Atif AK4,Islam Salman U5,Subhan Fazli3

Affiliation:

1. Department of Microbiology, Hazara University Mansehra, Mansehra, 21300, Pakistan

2. Department of Microbiology, Kohat University of Science & Technology (KUST), Kohat, 26010, Pakistan

3. Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, 46000, Pakistan

4. Department of Pharmacognosy, Lahore College for Women University, Lahore, 54600, Pakistan

5. Department of Pharmacy, CECOS University, Peshawar, 25000, Pakistan

Abstract

Aim: The current research aims to design effective strategies to enhance the body's immune system against pathogenic bacteria. Methods: Skin commensals were isolated, identified and cultured in fish collagen peptides (FCPs). Results: After culturing in FCP, the skin commensals were used in a dose-dependent manner for Staphylococcus aureus in a dual-culture test, which showed significant growth inhibition of the pathogenic bacteria, which concluded that FCP induced the immune defense system of skin microbiota against pathogenic strains. Conclusion: Results have validated that fish collagen peptide plays a vital role in the growth of selected human skin flora and induces more defensive immunity against pathogenic S. aureus bacteria in dual-culture experimentation.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

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