Resveratrol as a potential broad-spectrum compound for cancer treatment

Abstract

There is a need to shift the paradigm of cancer therapeutic approach. The severe adverse side effects, drug resistanceand unaffordable price plagued with chemotherapeutic drugs has spurred the development of “dirty drug”. Natural products,specifically phytochemicals, have gained much attention due to their ability to target multiple interconnected pathways.Resveratrol (RSV), the stilbenes found in red wine, is one of the phytochemicals that exhibits various pharmacologicaltherapeutic effects including cancer. In this review, we highlighted RSV as a potential “broad-spectrum” anticancer compound,by summarising its targeting mechanisms in the pathways relevant to the cancer hallmarks.