Аntiretroviral therapy for HIV in clinical practice-Reference-Cited by-同舟云学术

Аntiretroviral therapy for HIV in clinical practice

Published:2020-11-12 Issue:3 Volume:12 Page:59-68
ISSN:2077-9828
Container-title:HIV Infection and Immunosuppressive Disorders
language:
Short-container-title:VIČ-infekc. immunosupr.

Author:

Lukashova L. V.¹,Deev I. A.¹,Kulikov Ye. S.¹,Plotnikova Yu. K.²,Skudarnov S. E.³,Chernova O. Je.⁴,Abdullova N. F.⁵,Chernov A. S.⁶,Dmitriev S. V.⁷,Pimenov I. D.¹,Remeeva Ye. V.¹,Filatova Ye. N.¹,Tagina Ye. K.¹,Tyufilin D. S.¹

Affiliation:

1. Siberian State Medical University

2. Center for the Prevention and Control of AIDS in Irsutsk

3. Center for the Prevention and Control of AIDS in Krasnoyarsk

4. Center for the Prevention and Control of AIDS in Samara

5. Center for the Prevention and Control of AIDS in Ulyanovsk

6. Center for the Prevention and Control of AIDS in Tomsk

7. Department of Health in Tomskaya Oblast

Abstract

Objective: this study aims to analyze the use of antiretroviral therapy and its efficacy in HIV-infected patients in 5 regions of Russian Federation.Materials and methods: the research protocol included a retrospective analysis of the regional Centers for the Prevention and Control of AIDS registers and medical records of patients. Inclusion criteria were a veriﬁed diagnosis of HIV infection. The ﬁrst group included patients (n=1161) receiving antiretroviral therapy regimens at the latest by 01/01/2015, the second group included patients with no antiretroviral therapy before 01/01/2015 (n=1366). The groups were compared with each other by socio-demographic indicators and characteristics of HIV infection, including infection routes, stage of the disease and its natural course.Results: Group I showed a higher prevalence of patients with an undetectable viral load (60,7%) comparing to group II (p<0,05) where a low (70,9%) and high (8,5%) viral load was observed. There was a dynamic decrease in patients’ numbers with severe immunodeﬁciency by 12.6% and an increase in the average amount of CD4+ in group I.

Publisher

Baltic Medical Education Center

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health,Immunology

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