Subcutaneous Sweet Syndrome Successfully Treated With Ustekinumab in a Patient With Ulcerative Colitis-Reference-Cited by-全球学者库

Subcutaneous Sweet Syndrome Successfully Treated With Ustekinumab in a Patient With Ulcerative Colitis

Published:2022-11 Issue:11 Volume:9 Page:e00881
ISSN:2326-3253
Container-title:ACG Case Reports Journal
language:en
Short-container-title:ACG Case Rep J

Author:

Hu Kelly A.¹,Shen Jeanne²,Rieger Kerri³,Wei Mike T.¹⁴,Gubatan John¹⁴^ORCID

Affiliation:

1. Department of Medicine, Stanford University School of Medicine, Stanford, CA

2. Department of Pathology, Stanford University School of Medicine, Stanford, CA

3. Department of Dermatology, Stanford University School of Medicine, Stanford, CA

4. Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, CA

Abstract

ABSTRACT Ustekinumab, an inhibitor of the interleukin-12/23 pathway, received Food and Drug Administration (FDA) approval in 2019 for induction and maintenance therapy in patients with moderate-to-severe ulcerative colitis (UC). Data regarding the efficacy of ustekinumab in the treatment of extraintestinal manifestations of UC are unclear. Sweet syndrome, an acute febrile neutrophilic dermatosis, is a cutaneous manifestation of inflammatory bowel disease that parallels disease activity. In this study, we present the first case of subcutaneous Sweet syndrome with sterile osteomyelitis in a patient with UC successfully treated with ustekinumab.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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