Amanita Mushroom Toxin Poisoning in Los Angeles County

Author:

Jobin Parker G.1ORCID,Stewart Connor1,Vipani Aarshi2,Perez-Alvarez Ingrid3,Pepkowitz Samuel3,Klapper Ellen3,Berg Anders3,Stillman Kaytlena4,Torbati Sam4,Kuo Alexander25,Trivedi Hirsh25,Yang Ju Dong25,Steinberger Jonathan6,Van Allan Richard J.6,Friedman Oren7,Cardoza Kathryn1,Ayoub Walid S.25

Affiliation:

1. Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

2. Karsh Division Gastroenterology & Hepatology, Cedars-Sinai Medical Center, Los Angeles, CA

3. Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

4. Department of Emergency Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

5. Comprehensive Transplant Center, Cedars-Sinai Medical Center, Los Angeles, CA

6. Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA

7. Division of Pulmonary & Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA

Abstract

ABSTRACT Mushroom (amatoxin) poisoning from ingestion is a rare but life-threatening medical emergency characterized by gastrointestinal symptoms before progression to multisystem organ failure in severe cases. Many therapies of amatoxin intoxication have been described, including supportive care, medical therapies, detoxification strategies, and liver transplant. The evidence supporting these therapies remains limited due to the rarity of amatoxin poisoning and challenge of a timely diagnosis. We report a case of amatoxin poisoning in Los Angeles causing severe liver injury without acute liver failure treated successfully using medical therapies, gallbladder drainage, and plasma exchange.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

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