Evaluating a Novel, Portable, Self-Administrable Device (“Beacon”) That Measures Critical Flicker Frequency as a Test for Hepatic Encephalopathy-Reference-Cited by-同舟云学术

Evaluating a Novel, Portable, Self-Administrable Device (“Beacon”) That Measures Critical Flicker Frequency as a Test for Hepatic Encephalopathy

Published:2023-02-03 Issue:6 Volume:118 Page:1096-1100
ISSN:0002-9270
Container-title:American Journal of Gastroenterology
language:en
Short-container-title:Am J Gastroenterol

Author:

Vutien Philip¹²^ORCID,Li Richard³,Karkar Ravi³⁴,Munson Sean A.⁵,Fogarty James³,Walter Kara¹,Yacoub Michael¹,Ioannou George N.¹²

Affiliation:

1. University of Washington, Division of Gastroenterology and Hepatology, Seattle, Washington, USA;

2. Department of Medicine Veterans Affairs Puget Sound Healthcare System and University of Washington, Seattle, Washington, USA;

3. Paul G. Allen School of Computer Science & Engineering, University of Washington, Seattle, Washington, USA;

4. Manning College of Information and Computer Sciences, University of Massachusetts Amherst, Amherst, Massachusetts, USA;

5. Human Centered Design & Engineering, University of Washington, Seattle, Washington, USA.

Abstract

INTRODUCTION: We compared critical flicker frequency (CFF) thresholds obtained using a novel portable device “Beacon” with thresholds from the commercially available Lafayette Flicker Fusion System (Lafayette-FFS) in patients with cirrhosis. METHODS: One hundred fifty-three participants with chronic liver disease underwent CFF testing using Beacon and Lafayette-FFS with a method-of-limits and/or forced-choice protocol. RESULTS: Beacon demonstrated excellent test-retest reliability (intraclass correlation 0.91–0.97) and good correlation with the Lafayette-FFS values (intraclass correlation 0.77–0.84). Forced-choice CFF were on average 4.1 Hz higher than method-of-limits descending CFFs. DISCUSSION: Beacon can be self-administered by patients with chronic liver disease and cirrhosis to measure CFF, a validated screening test for minimal hepatic encephalopathy.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Gastroenterology,Hepatology

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